BME-Biomedical Engineering

This is an archived copy of the 2021-2022 catalog. To access the most recent version of the catalog, please visit https://ou-public.courseleaf.com/.

BME 2333. Biomedical Engineering Fundamentals.3 Credit Hours.

Prerequisite: Majors only; MATH 1823 or 1914; MATH 2423 or 2924; CHEM 1315 or 1335; CHEM 1415 or 1435; and PHYS 2514; all five courses with a grade of B or better. Introduction to material, energy, charge, and momentum balances in biological systems. Steady state and transient conservation equations for mass, energy, charge, and momentum will be derived and applied using basic mathematical principles, physical laws, stoichiometry, and thermodynamic properties. (F)

BME 2433. Signals and Systems for Biomedical Engineering.3 Credit Hours.

Prerequisite: BME 2333; ECE 2723 or concurrent enrollment; course is not open to freshmen. Students learn circuits and linear systems concepts necessary for analysis and design of biomedical systems. Theory is motivated by examples from biomedical engineering. Topics covered include electrical circuit fundamentals, operational amplifiers, frequency response, electrical transients, impulse response, transfer functions, and convolution, all motivated by circuit and biomedical examples. Elements of continuous time domain-frequency domain analytical techniques are developed. (Sp)

BME 2970. Special Topics/Seminar.1-3 Credit Hours.

1 to 3 hours. Prerequisite: May be repeated; maximum credit nine hours. Special topics or seminar course for content not currently offered in regularly scheduled courses. May include library and/or laboratory research and field projects. (Irreg.)

BME 3111. Bioimaging Lab.1 Credit Hour.

Prerequisite: ISE 3293; completion or concurrent enrollment in BME 3113; majors only. Hands-on lab that teaches students technical skills associated with bioimaging. Lab components include hypothesis testing and analysis, computer simulation, lab safety and instrument training, and technical communication. (F, Sp)

BME 3113. Bioimaging.3 Credit Hours.

Prerequisite: BME 2333; BME 2433; PHYS 2524 and MATH 3113. Introduction to medical imaging techniques such as x-ray, computed tomography, magnetic resonance, and ultrasound. (F, Sp)

BME 3121. Biotransport Lab.1 Credit Hour.

Prerequisite: ISE 3293; completion or concurrent enrollment in BME 3123; majors only. Hands-on lab that teaches students technical skills associated with biotransport. Lab components include hypothesis testing and analysis, computer simulation, lab safety and instrument training, and technical communication. (F, Sp)

BME 3123. Biotransport.3 Credit Hours.

Prerequisite: BME 2333; PHYS 2524 and MATH 3113. Covers key transport concepts in biomedical engineering. Emphasis is put on mass and momentum transport with applications related to biology, medical science and biotechnology. (F, Sp)

BME 3131. Bioelectricity Lab.1 Credit Hour.

Prerequisite: ISE 3293; completion or concurrent enrollment in BME 3133; majors only. Hands-on lab that teaches students technical skills associated with electrobiology. Lab components include hypothesis testing and analysis, computer simulation, lab safety and instrument training, and technical communication. (F, Sp)

BME 3133. Bioelectricity.3 Credit Hours.

Prerequisite: BME 2333; 2433; PHYS 2524 and MATH 3113. The electrophysiology of excitable cells from a quantitative perspective. Topics include the ionic basis of action potentials, quantitative models for nerve and muscle including the Hodgkin-Huxley equations, impulse propagation, synaptic dynamics, source-field relationships, and an introduction to functional electrical stimulation. (F, Sp)

BME 3141. Biomechanics Lab.1 Credit Hour.

Prerequisite: ISE 3293; completion or concurrent enrollment in BME 3143; majors only. Hands-on lab that teaches students technical skills associated with biomechanics. Lab components include hypothesis testing and analysis, computer simulation, lab safety and instrument training, and technical communication. (F, Sp)

BME 3143. Biomechanics.3 Credit Hours.

Prerequisite: BME 2333; PHYS 2524 and MATH 3113. Analysis of human motion, evaluation of tissue solid mechanics, and identification of principal planes and stresses. (F, Sp)

BME 3151. Molecular, Cellular and Tissue Engineering Lab.1 Credit Hour.

Prerequisite: ISE 3293; completion or concurrent enrollment in BME 3153; majors only. Hands-on lab that teaches students technical skills associated with molecular, cell, and tissue engineering. Lab components include hypothesis testing and analysis, computer simulation, lab safety and instrument training, and technical communication. (F, Sp)

BME 3153. Molecular, Cellular and Tissue Engineering.3 Credit Hours.

Prerequisite: BME 2333, MATH 3113 and BIOL 1124. Application of engineering methods to study, measure, repair, or replace biological functions at the molecular, cellular, or tissue-level length scales. (F, Sp)

BME 3161. Biomedical Micro-/Nano-Technology Lab.1 Credit Hour.

Prerequisite: ISE 3293; completion or concurrent enrollment in BME 3163; majors only. Hands-on lab that teaches students technical skills associated with BME micro/nanotechnology. Lab components include hypothesis testing and analysis, computer simulation, lab safety and instrument training, and technical communication. (F, Sp)

BME 3163. Biomedical Micro-/Nano-Technology.3 Credit Hours.

Prerequisite: BME 2333; PHYS 2524; MATH 3113; majors only. Introduction to micro/nanotechnology in biomedical settings, including micro/nanotechnologies used to investigate biological systems, physiological responses to nanotherapeutics, and first principles of microfluidics and microfabrication. (F, Sp)

BME 3171. Biomedical Engineering Lab 1.1 Credit Hour.

Prerequisite: Junior standing; ISE 3293 or ECE 2523; completion or concurrent enrollment in BME 3143; majors only. Hands-on lab that teaches students technical skills associated with BME biomechanics, and also includes topics such as bioelectricity and molecular, cellular & tissue engineering. Lab components include hypothesis testing and analysis, computer simulation, lab safety and instrument training, and technical communication. (F)

BME 3181. Biomedical Engineering Lab 2.1 Credit Hour.

Prerequisite: Junior standing; BME 3171; concurrent enrollment in BME 3123 and BME 4813; majors only. Hands-on lab that teaches students technical skills associated with BME biotransport and quantitative physiology, and also includes topics such as bioimaging and micro/nanotechnology. Lab components include hypothesis testing and analysis, computer simulation, lab safety and instrument training, and technical communication. (Sp)

BME 3233. Biomaterials.3 Credit Hours.

Prerequisite: BIOL 1124, BME 2333, PHYS 2524, and BME 3143; majors only; permission of instructor. Introduction to materials used in biomedical environment, the design and use of implantable materials, such as metals, polyethylene, ceramics, and composites, biocompatibility, test methods, and tissue growth on biomaterials. (F)

BME 3440. Mentored Research Experience.3 Credit Hours.

0 to 3 hours. Prerequisites: ENGL 1113 or equivalent, and permission of instructor. May be repeated; maximum credit 12 hours. For the inquisitive student to apply the scholarly processes of the discipline to a research or creative project under the mentorship of a faculty member. Student and instructor should complete an Undergraduate Research & Creative Projects (URCP) Mentoring Agreement and file it with the URCP office. Not for honors credit. (F, Sp, Su)

BME 3531. Bioinstrumentation Lab.1 Credit Hour.

Prerequisite: BME 2433, corequisite BME 3533; Majors only. Fundamental circuit elements and concepts include resistance, capacitance, inductance, op-amps, impedance, voltage, current, power, and frequency. Fundamental analog measurement concepts include adequate bandwidth and amplitude and phase linearity. Examples of medical measurements and devices are included for the fundamental circuit and measurement concepts covered above. Introduction of laboratory instruments used to simulate measurements of and direct measure physiological events. (F)

BME 3533. Biomedical Instrumentation.3 Credit Hours.

Prerequisite: BME 2433. Measurement and analysis of biopotentials and biomedical transducer characteristics; electrical safety applications of FET's; integrated circuits, operational amplifiers for signal processing and computer interfacing; signal analysis and display on the laboratory minicomputer. (Sp)

BME 3722. Numerical Methods in Biomedical Engineering.2 Credit Hours.

Prerequisite: C S 1213, MATH 3113 and BME 2333; majors only. Introduces principles and techniques of numerical analysis of biomedical engineering problems. Covers numerical methods of integration, differentiation, interpolation, curve fitting, data analysis, sampling and estimation, error analysis, analysis of ordinary differential equations, numerical modeling of biomedical engineering systems, symbolic computation, and scientific visualization. (F)

BME 3980. Honors Research.1-3 Credit Hours.

1 to 3 hours. Prerequisite: admission to Honors Program. May be repeated; maximum credit 6 hours. Selected students work with individual faculty members on research problems in biomedical engineering. (F, Sp, Su)

BME 4013. Introduction to Medical Device Design.3 Credit Hours.

(Slashlisted with BME 5013; Crosslisted with AME 4013) Prerequisite: Junior standing or permission of instructor. Introduction to medical device design with emphasis on the entire procedure of developing a medical device from identifying the unmet medical need to product launching. Topics include marketing and technology survey, concept development, the biocompatible material, device prototype, bench test, in vitro/in vivo test, clinical trial and FDA regulation. No student may earn credit for both 4013 and 5013. (Sp)

BME 4050. Design Projects in Biomedical Engineering.3 Credit Hours.

0 to 3 hours. Prerequisite: Permission of Instructor. May be repeated; maximum credit 6 hours. This course is designed for students who are participating in design and project based experiences. This course is different from mentored research in that the student is expected to have completed a functioning prototype or design solution by the end of the experience. Credit hours may vary, based on the size, scope, and expectations of the project. (F, Sp)

BME 4281. Engineering Co-Op Program.1 Credit Hour.

(Crosslisted with AME, C S, CEES, CH E, ECE, ISE and EPHY 4281) Prerequisite: Departmental permission and junior standing. May be repeated; maximum credit 6 hours. The Co-Op program provides students an opportunity to enhance their education via career exploration in related professional work experiences. Course assignments help students articulate their experiences by completing journals; mid-term paper; final paper and/or final presentation. Faculty receive an evaluation from the student's Co-Op supervisor who monitors performance. Faculty collaborate with the Co-Op supervisor to ensure student success. (F, Sp, Su)

BME 4533. Neural Engineering.3 Credit Hours.

(Slashlisted with BME 5533) Prerequisite: BME 3113 or BME 3133 or concurrent enrollment, or instructor permission. Principles and technologies of applying engineering to neuroscience, including areas as neural tissue engineering, models of neural function, neural interface and neuromodulation technology. Examples of neural engineering systems focus on brain-controlled interface and prosthetic systems currently in development or produced commercially, neurofeedback and brain stimulation systems for treating disorders such as depression. MATLAB(R) programming is required. No student may earn credit for both 4533 and 5533. (F)

BME 4713. Biomedical Engineering Design I.3 Credit Hours.

Prerequisite: BME 3533 or concurrent enrollment; Senior standing in the BS in BME curriculum. Structured methodologies for designing systems or to interface with living systems. Creative design, analysis, selection, development, and fabrication of biomedical components and systems. (F)

BME G4813. Quantitative Physiology.3 Credit Hours.

Prerequisite: BME 3722, junior standing, and majors only. Introduces students to the mathematical and numerical techniques used to develop, solve, and analyze quantitative models of physiology systems. (Sp)

BME 4823. Biomedical Engineering Design II.3 Credit Hours.

Prerequisite: BME 4713. Development of team projects in biomedical engineering with emphasis on prototype development and quantitative analysis, and written and oral reporting of the outcome. Capstone. (Sp) [V].

BME 4970. Special Topics/Seminar.1-3 Credit Hours.

1 to 3 hours. Prerequisite: Senior standing or permission of instructor. May be repeated; maximum credit nine hours. Special topics or seminar course for content not currently offered in regularly scheduled courses. May include library and/or laboratory research and field projects. (Irreg.)

BME 4980. Senior Thesis.1-3 Credit Hours.

1 to 3 hours. Prerequisite: Senior standing, BME 3440 or BME 3980, and permission of instructor. The Senior Thesis is an option for seniors who are especially interested in research and/or intending to continue on to a PhD program. Students who have completed the first semester (fall of their senior year) and have satisfactorily passed the fall semester report will enroll in this course for the Spring of their senior year only. (Sp)

BME 5013. Introduction to Medical Device Design.3 Credit Hours.

(Slashlisted with BME 4013; Crosslisted with AME 5013) Prerequisite: Graduate standing or permission of instructor. Introduction to medical device design with emphasis on the entire procedure of developing a medical device, from identifying the unmet medical need to product launching. Topics include marketing and technology survey, concept development, the biocompatible material, device prototype, bench test, in vitro/in vivo test, clinical trial, and FDA regulation. No student may earn credit for both 4013 and 5013. (Sp)

BME 5113. Special Topics in Cancer.3 Credit Hours.

Prerequisite: Graduate standing and permission of instructor. Students will develop an appreciation of the tools available at hand to dissect the molecular mechanisms controlling cancer development such that they can take this knowledge to the bench to develop their own graduate research. (Sp)

BME 5213. Biomechanics I.3 Credit Hours.

(Crosslisted with AME 5213) Prerequisite: AME 3143 and AME 3153 or permission of instructor. Introduction to physiological systems with emphasis on structure and function of tissues and organs; application of continuum mechanics to understanding of tissue and organ behavior at microscopic and macroscopic levels; viscoelastic behavior at microscopic and macroscopic levels; viscoelastic and solid biomaterials. (F)

BME 5233. Biomaterials.3 Credit Hours.

Prerequisite: Graduate standing, BME 3233, and permission of instructor. Introduction to materials used in biomedical environment, the design and use of implantable materials (such as metals, polyethylene, ceramics, composites), biocompatibility, test methods, and tissue growth on biomaterials. (Sp)

BME 5243. Biochemical Engineering.3 Credit Hours.

(Crosslisted with CH E 5243) Prerequisite: CH E 3123 or permission of instructor. Current bioprocesses for reaction and separation with emphasis on fundamental principles of chemical engineering, biochemistry, and microbiology. (Sp)

BME 5283. ImmunoEngineering.3 Credit Hours.

Prerequisite: Graduate standing or permission of instructor. The immune system plays a big role to maintain the homeostasis in our body. It provides the first reaction to external stresses, such as pathogens, biomaterials and implants, and cancer. Dysregulations in immune system can cause autoimmune diseases or determine our fate when we are exposed to external diseases. (Sp)

BME 5293. Transport in Biological Systems.3 Credit Hours.

(Crosslisted with CH E 5293) Prerequisite: CH E 3123 or permission of instructor. Theoretical and practical aspects of transport phenomena in living organisms and biomedical technologies. Applications include hemorheology, drug delivery, extracorporeal circulation and artificial organs. (Irreg.)

BME 5363. Optical Engineering.3 Credit Hours.

(Crosslisted with ECE 5363) Prerequisite: ECE 3793. Underlying theory and design of optical systems. Interference, diffraction and coherence phenomena will be examined as a basis for studying the limits of optical system performance. Other topics include a detailed study of polarization, the interaction of light with various media and geometrical optics. (Sp)

BME 5373. Tissue Engineering.3 Credit Hours.

(Crosslisted with CH E) Prerequisite: graduate standing or permission of instructor. Examines the background and recent advances in the science of combining multiple cell types with an appropriate support to provide a construct that can replace or support damaged tissue. (Irreg.)

BME 5413. Nanomedicine.3 Credit Hours.

Prerequisite: BME 3163 and permission of instructor. Introduction to nanomaterials used in preclinical and clinical stages; the design, application, and evaluation of nanomaterials to diagnose and treat diseases, including cancer. (Sp)

BME 5443. Neural System and Rehabilitation Engineering.3 Credit Hours.

Prerequisite: Graduate standing or permission of instructor. Advanced knowledge of neural control of movement, musculoskeletal system, and movement impairment and disability will be discussed. Topics include the frontiers of rehabilitation engineering, including assistive technologies, brain-computer interfaces, non-invasive brain stimulation, regenerative rehabilitation, and machine learning in rehabilitation. The students will learn writing skills for NIH/AHA aims page for research projects in the field of rehabilitation (Sp)

BME 5533. Neural Engineering.3 Credit Hours.

(Slashlisted with BME 4533) Prerequisite: Graduate standing or permission of instructor. Principles and technologies of applying engineering to neuroscience, including neural tissue engineering, models of neural function, neural interface, and neuromodulation technology. Examples of neural engineering systems focus on brain-controlled interface and prosthetic systems currently in development or produced commercially, and neurofeedback and brain stimulation systems for treating disorders such as depression. MATLAB(R) programming is required. No student may earn credit for both 4533 and 5533. (F)

BME 5853. Biomedical Signals and Systems.3 Credit Hours.

(Crosslisted with ECE 5853) Prerequisites: ECE 3723 and ECE 3793, or equivalent course in electrical circuits and signal processing, or permission of instructor. Comprehensive coverage of topics related to signals in humans. Emphasis on using engineering tools to interpret signals and underlying physiological principles. Focus on emerging engineering technologies, physiological knowledge and clinical application. (Sp)

BME 5863. Bioinstrumentation.3 Credit Hours.

(Crosslisted with ECE 5863) Prerequisite: ECE 4213 or permission of the instructor. A comprehensive coverage of topics related to principles, applications, and design of medical instruments widely used in hospitals and clinical researches. Emphasis is placed on general design concepts, discussions on a great variety of medical devices, and medical device safety issues. Materials cover different levels and various aspects of human systems, such as heart, brain, circulation, respiration. (F, Sp)

BME 5960. Directed Readings.1-3 Credit Hours.

1 to 3 hours. Prerequisite: graduate standing or permission of department. May be repeated; maximum credit sic hours. Directed readings and/or literature reviews under the direction of a faculty member. (Irreg.)

BME 5970. Special Topics/Seminar.1-3 Credit Hours.

1 to 3 hours. Prerequisite: Graduate standing or permission of instructor. May be repeated; maximum credit nine hours. Special topics or seminar course for content not currently offered in regularly scheduled courses. May include library and/or laboratory research and field projects. (Irreg.)

BME 5971. Seminar in Biomedical Engineering Research.1 Credit Hour.

Prerequisite: Graduate standing and BME majors only; May be repeated with change of content; maximum credit 6 hours. The department will invite speakers and the graduate students to present their ongoing research. Students will learn the frontiers in biomedical engineering and relevant fields and will have the opportunity for discussion with leading scientists. Students will also be encouraged to present their own research work and get feedback from faculty and peers. (F, Sp)

BME 5973. Special Topics in Electrical and Computer Engineering.3 Credit Hours.

(Crosslisted with ECE 5973) Prerequisite: Graduate standing and permission of instructor. May be repeated with change of content; maximum credit 12 hours. Selected topics of current research interest not covered by regularly scheduled coursework. (F, Sp, Su)

BME 5980. Research for Master's Thesis.2-6 Credit Hours.

2 to 6 hours. Prerequisite: graduate standing or permission by instructor. May be repeated; maximum credit toward degree six hours. Directed research culminating in the completion of the master's thesis. (F, Sp, Su)

BME 5990. Independent Study.1-3 Credit Hours.

1 to 3 hours. Prerequisite: graduate standing or permission by instructor. May be repeated with change of subject matter; maximum credit six hours. Contracted independent study for a topic not currently offered in regularly scheduled courses. Independent study may include library and/or laboratory research and field projects. (Irreg.)

BME 6213. Optical Information Processing.3 Credit Hours.

(Crosslisted with ECE 6213) Prerequisite: ECE 5213 and ECE 5353. Application of Fourier transforms, linear systems, and diffraction theory to the analysis of optical systems. Emphasis is on the use of optical systems for information processing, including image enhancement, pattern recognition, data processing, optical switching, and computing. (F)

BME 6960. Directed Readings.1-3 Credit Hours.

1 to 3 hours. Prerequisite: graduate standing or permission of instructor. May be repeated; maximum credit six hours. Directed readings and/or literature review under the direction of a faculty member. (Irreg.)

BME 6970. Advanced Topics in Bioengineering.1-6 Credit Hours.

1 to 6 hours. Prerequisite: graduate standing or instructor permission. May be repeated with change of topic; maximum credit towards degree six hours. Selected topics of current faculty research interest at the PhD level not covered by regularly scheduled courses. (Irreg.)

BME 6980. Research for Doctoral Dissertation.2-16 Credit Hours.

2 to 16 hours. Prerequisite: graduate standing or permission of instructor. May be repeated. (F, Sp, Su)

BME 6990. Independent Study.1-3 Credit Hours.

1 to 3 hours. Prerequisite: graduate standing and permission of instructor. May be repeated; maximum credit nine hours. Contracted independent study for a topic not currently offered in regularly scheduled courses. Independent study may include library and/or laboratory research and field projects. (Irreg.)